A New Approach to
Diabetes Management

Cutting edge method designed to enhance recovery and deliver advanced healing techniques.

Diabetes In America Today

Did you know diabetes and its associated complications affect over 34 million Americans? An additional 88 million Americans are prediabetic, and in 2019, diabetes caused $476 billion in healthcare expenditures.

Its Time For A Change

Diabetes has afflicted people for thousands of years; this broadly misunderstood and draining disease causes many people to feel overwhelmed by the unrelenting symptoms.

Finally, with PIR (Physiologic Insulin Resensitization), we can introduce hope. With PIR treatment, many individuals with diabetes and other metabolic disorders have experienced relief and improvement from the following:

  • Chronic Pain
  • Fatigue
  • Weight Gain
  • Weight Loss
  • Blurred Vision
  • Headaches
  • Brain Fog
  • Sexual Performance
  • Wound Healing Ability
  • Dry Mouth and Dry Skin
  • Numbness and Tingling
  • Overeating
  • Frequent Urination
  • And much more!

What Is It & How Does It Work?

What Is Physiologic Insulin
Rensensitization (PIR)®?

Physiologic Insulin Resensitization (PIR)® is an innovative, multi-patented, physician-directed system that provides an inventive way of providing customized patient care where insulin is administered as a hormone rather than a drug. IV access is connected to a precision infusion pump programmed to deliver insulin in a way that simulates normal glucose metabolism. Blood sugar can now more readily enter each cell and be converted into energy. By using insulin in this manner, we can bio-mimic normal glucose metabolism. This treatment process can show improvement in:  

  • Support Insulin Sensitivity: By delivering insulin in a physiological manner, there’s potential for improved insulin response

  • Facilitate Glucose Uptake: This method may promote greater glucose entry into cells, which is essential for energy production

  • Aid In Cellular Function: by potentially optimizing glucose utilization, it may support the body’s ability to repair and regenerate tissues

By taking the sugar within the bloodstream and pushing it into the cells, the human body can begin to properly functionary allowing damaged tissues and organs to grow, repair, and regenerate. 

How Does PIR Work?

  • Insulin as a Hormone vs. a Drug – The key is using insulin as a hormone rather than a drug.


  • Physiologic Administration – By mimicking physiologic secretion profiles, insulin receptor activity is upregulated, and insulin resistance is reduced. Improved sensitivity facilitates carbohydrate processing, improved metabolism, and greater ATP production. This allows damaged tissues and organs to repair and regenerate.


  • Insulin Sensitization – precision dosing of insulin enhances insulin sensitization by maintaining stable blood glucose levels and prevents hyperglycemia. This individualized approach allows for optimal insulin signaling, promoting efficient glucose uptake by cells.


  • Cellular Health – With increased cellular sensitivity of glucose intake, the next step is improved metabolic function. Improved uptake of glucose into the cells allows your cells to utilize the glucose, and form it into energy it desperately needed. As a result, metabolic function occurs more efficiently, thus improving energy utilization and overall cellular health -while minimizing the risk of complications associated with diabetes.

Clinical Research & Publications

  • A Receptor Story: Insulin Resistance Pathophysiology and Physiologic Insulin Resensitization’s Role as a Treatment Modality (International Journal of Molecular Sciences)

  • Physiologic Insulin Desensitization as a Treatment Modality for Insulin Resistance Pathophysiology (International Journal of Molecular Sciences)

  • Physiologic hormone administration improves HbA1C in Native Americans with type 2 diabetes: A retrospective study and review of insulin secretion and action (WILEY)

  • Improved HOMA-IR Insulin Sensitivity and Glycemic Control Utilizing Physiologic Insulin Resensitization (Archives of Clinical and Medical Case Reports)

  • Improved Kidney Function Following Physiologic Insulin Resensitization Treatment Modality (Journal of Endocrinology and Disorders)

  • Case Series: Reversal of Diabetic Neuropathy Utilizing Physiologic Insulin Resensitization

  • Case Series: Reversal of diabetic retinopathy in two patients following the use of physiologic insulin Resensitization (Journal of Diabetes and Its Complications)

  • Dynamic diabetes solutions: physiologic insulin resensitization (Medical & Clinical Research)

  • Adjunctive Care in Sequential Diabetic Foot Wounds: Case Study (American Journal of Biomedical Science & Research)

  • Efficacy of Physiologic Insulin Resensitization as a Treatment for Insulin Resistance Pathophysiology

  • Physiologic Insulin Desensitization Lowers Cost In Patients with Diabetes and Kidney Disease

Info For Our Patients

/

Are You Ready To Get Started?

Qualifying Exam & Lab Work

Treatment
Begins

Consultation

Treatment Plan Determination

Qualifying Exam & Lab Work

Treatment
Begins

Diabetic and Wound
Care Programs

Conveniently
Located

Common Questions & Concerns

PIR is an evolutionary form of therapy that uses insulin as a hormone instead of a drug. PIR uses precision dosing patters of insulin that is consistent with normal hormone secretion- this pattern resembles the body’s natural signaling pathway.

  • During a 2–3-hour IC therapy session, the proper dose of insulin is given (as a hormone) to help the body reduce resistance, while simultaneously bringing your levels back into balance,
  • As the patient’s insulin levels improve , healthcare providers can titrate other medications to optimize treatment regimens further. The use of PIR permits the ability to lower the dosing of subcutaneous insulin and other diabetic medications.
    • Reduces insulin resistance
    • Increases the amount go blood sugar entering the cell
    • Increase the conversion of sugar into energy

Some patients can experience immediate relief, even after the very first treatment. Your healthcare provider Weill determine the total number of treatments they feel will give you the most benefit and create a custom care plan for your unique health situation. Normally, treatments are done about 1x per week.

During your first consultation with your healthcare practitioner, both you and your provider can determine a course of treatment best suited for your individual and unique situation. Most of our patients see results after a few treatments and continue to want the PIR treatments after already completing their initial course. Most patients will need to come in about 1x per week, until their symptoms are reduced.

Treatments may be covered by Medicare and PPO insurance providers. Please contact the clinic, and we will be happy to confirm your insurance and , if any, out of pocket costs. If you do not have insurance or are covered under a plan we do not accept, please give us a call so we can discuss other payment options.

Our treatments, including PIR may be covered by Medicaid/Medicare and PPO insurance. Give us a call, we would be happy to confirm your insurance coverage for you.

We are currently accepting new patients! Come right in or give us a call! We’ll be happy to schedule your initial consultation.

Get in touch